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In the Lab.

R&D / Pipeline

UPA Contraception

HRA Pharma is developing two UPA contraceptive products (UPAC-ring and UPAC-IUS) based on the molecule ulipristal acetate, a new chemical entity which modulates the activity of the progesterone receptor.

The UPA Contraception project consists of formulating ulipristal acetate for local administration via a number of novel delivery systems so it can be used as a method of continuous contraception. UPA Contraception products promise to bring true innovation to the field of contraception, as a locally delivered, non-estrogenic hormone that enables good cycle control. These projects are being pursued in collaboration with the Population Council, a leader in the development of innovative contraceptive technologies.

  • UPA C-ring

    UPA C-ring is a vaginal ring that diffuses UPA locally in a continuous fashion.
    UPA C-ring is currently undergoing Phase II clinical trials.
  • UPA C-IUS

    UPA C-IUS is an intrauterine device that diffuses UPA to the uterus for the prevention of pregnancy. UPA C-IUS is currently in the preclinical phase.